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The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product
Compared with regular HaloTag Ligand
Product Name Mal-Lys(m-PEG4)-Val-Ala-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C42H56N6O15 Molecular Weight 884
The excitation and emission wavelengths of rhodamine 6G fall between those of fluorescein and tetramethylrhodamine derivatives
Product Name Lenalidomide-PEG2-C2-amine HCl Synonyms Lenalidomide-4'-PEG2-C2-amine HCl CAS Number 2360523-27-7 Related CAS Molecular Formula C19H27ClN4O5 Molecular Weight 426
DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE pomalidomide The strain in DBCO’s cyclooctyneSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
