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Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg References

SKU 80648920072
4.1
EUR445.00 EUR475.00

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Description

References

The taselisib-induced degradation of mutant p110a protein is ubiquitin-mediated and proteasome-dependent

Product Name: Cy3 azide trisulfo Synonyms: Cy3 azide

BODIPY FL VH032 is a high-affinity fluorescent probe for the von Hippel–Lindau (VHL) protein

Product Name Thalidomide-C3-OH Synonyms Thalidomide-4'-C3-OH CAS Number 2357113-44-9 Related CAS Molecular Formula C16H16N2O5 Molecular Weight 316

Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg ReferencesSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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