DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) piperidine Product Name Pomalidomide-5'-PEG1-C2-acid Synonyms CAS

Product Name Pomalidomide-5'-PEG1-C2-acid Synonyms CAS Number 2412056-43-8 Related CAS Molecular Formula C18H19N3O7 Molecular Weight 389

CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity

833 Purity (HPLC) >= 95% Solubility DMSO

Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

making it ideal for live-cell imaging and long-term studies

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) piperidine Product Name Pomalidomide-5'-PEG1-C2-acid Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to